Regenerative Foot, Ankle & Lower-Leg Medicine · Ohio · Chicago · Puerto Rico · South Carolina · South Dakota
Move better. Live with less pain.
A national institute of physician specialists using your body’s own biology — stem cells, exosomes, PRP and more — to treat foot, ankle and lower-leg conditions without surgery.
The Science of Healing
Regenerative medicine, focused entirely on the lower extremity.
We treat the cause of foot, ankle and lower-leg pain — not just the symptom — so you can get back on your feet without surgery.
Our physicians (DPM) unite leading lower-extremity regenerative-medicine specialists across the country to advance patient outcomes through collaborative excellence.
About the Institute
What we offer
Regenerative Treatments
Orthobiologic therapies, combined precisely for your condition.
Stem Cell Therapy
Cell-based regeneration for foot, ankle & lower-leg tissue.
Learn moreExosome Therapy
Signaling-based repair for tendons, ligaments & pain.
Learn morePlatelet-Rich Plasma (PRP)
Your own platelets to accelerate tissue healing.
Learn morePeptide Therapy
Targeted peptides that support recovery and repair.
Learn moreBone Marrow Concentrate (BMAC)
Marrow-derived cells, concentrated and guided.
Learn moreCombination Treatments
Protocols combined precisely for your condition.
Learn moreBy condition
Where does it hurt?
Start with the problem that’s holding you back.
Plantar Fasciitis
Chronic heel pain and arch strain.
Learn moreAchilles Tendonitis
Tendon pain, stiffness and degeneration.
Learn moreAnkle Arthritis
Degenerative joint pain and stiffness.
Learn moreNerve Pain
Neuropathy and nerve entrapment of the lower extremity.
Learn moreCartilage Injury
Osteochondral defects and cartilage damage.
Learn moreSports Injury
Lower-leg, ankle and foot injuries in active people.
Learn moreOur difference
One national network.
One standard of care.
Board-certified, fellowship-trained foot & ankle physicians. In-office, non-surgical treatment using your own biology — with a collaborative network advancing what regenerative medicine can do for the lower extremity.
Meet the physicians
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5
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8
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Non-surgical
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DPM-led
Our team
Care from trusted hands
Board-certified foot & ankle physicians across five locations.
Stephen Frania, DPM
Medical Director (Ohio); board-certified by the American Board of Foot and Ankle Surgery; fellowship director.
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Edgardo R. Rodriguez-Collazo, DPM
Medical Director (Chicago); reconstructive podiatric surgeon focused on lower-extremity nerve surgery and orthoplastic reconstruction.
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Kyle McKray Smith, DPM
Board-certified by the American Board of Foot and Ankle Surgery and the American Board of Podiatric Medicine.
View profileEdmond Medina Hernández, DPM
Member of the American Microsurgical Orthoplastic Society (AMOS) and the Chicago Lower Extremity Surgical Symposium Foundation (CLESF).
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Laurence Cane, DPM
Board-certified by the American Board of Foot and Ankle Surgery and a board-certified wound care specialist.
View profileShannon Carmignani, DPM
Regenerative medicine provider licensed in South Carolina.
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Gabriel Rodriguez, DPM
Diplomate of the American Board of Multiple Specialties in Podiatry; board-certified in Primary Care.
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Rachel Robinson, DPM
Board-qualified with the American College of Foot and Ankle Surgeons.
View profileIn their words
What our patients say
“I have been working with this group for the past year and they are always very helpful, friendly, and professional.”
“One of the top in Ohio for sure.”
“The staff were very kind and when I called for support they were helpful and got me the information I needed ASAP.”
Find a location near you
Regenerative foot & ankle care in Ohio, Chicago and Puerto Rico — with providers in South Carolina and South Dakota.
See whether you’re a candidate for regenerative treatment.
Free consultations at all five locations.